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Can Ecstasy cause permanent anxiety/panic/depression?

Question:
Has anyone had this happen to them or seen it happen to others? I believe it happened to me. I'm surprise to not have seen more discussion of this on thiswebsites. I was a run of the mill, mildly anxious, mildly depressed person for years, although sometimes just fine for years. Then I took ecstasy 5 times over about 6 months. During the four months after the last time I took any, I gradually got worse and worse, until I became suicidally anxious with major depersonalization. I now require 2mg alprazolam every day where before I took no medication. Maybe it was just my time to snap, but I can't think of any other reason why I would have, and the 4 month time frame fits some research that has been published by one of the leading anti-MDMA scientists. There is alot of controversy on this because some say Ecstasy can help with mental illness, and I know there are tons of people out there taking it every weekend, and so far there doesn't seem to be an epidemic of anxiety breaking out among young people. Maybe it only happens to people who are already on the edge of severe anxiety/depression. But I would just like to hear what anyone else has to say about it. Ecstasy caused my Generalized Anxiety Disorder - Don't ever use it, especially if you suffer any form of Anxiety/Depressive/Sleep Disorder


Answer:
Even if you convince one person not to try it, your warning will not be in vain. I saw the United States nationwide History Channel presentation on the history of illicit drug use, and it said that psychiatrists are scared of MDMA's ability to antagonize serotonin receptors PERMANENTLY. The people who use MDMA enough will most likely have to be on antidepressants for the rest of their lives. Interestingly, MDMA was first used in the '60s as a drug that couples could use to get closer to one another in sex. It was prescribed legally by psychologists. I'm not making this up.... A lot of kids that I knew in high school were depressed to begin with; they were the disenfranchised in society (the bookworm, the unattractive, the infirm). When they tried all sorts of drugs, I knew it wasn't just to have fun. It was a cry for help heeded by the wrong people, in this case, drug dealers. I've never done 'E' and don't intend to but I follow the papers and the drug info pages on the net. From what I know about 'E' you may not be getting 'E' at all. PMA has been sold as 'E'(PMA can be real bad news). Meth has been sold as MDMA. BTW don't believe the myth that heroin is being sold as MDMA. Doesn't make sense. Do you know what you're actually getting? Sometimes a mix is sold as 'E'. And of course 'E' is also sold as 'E'. -- Sure ecstasy can cause depression. Its bad stuff, especially when used repetively over time. Its not physiologically addictive in the sense that cocaine or heroin are. However, it has the potential to scramble brain chemistry like all psychedelic drugs can do. Ecstasy is a psychedelic drug. I dont really know of any thing that can fix what ecstasy does to you. My guess would be maybe ECT might be the best thing to blast your brain back to normal or semi normal. Sometimes it takes STRONG measures to whip that depression problem. I really feel bad for you and I know there are a lot of people out there getting messed up by using illicit recreational drugs and even booze. These all have the potential to really screw up your brain and CNS, especially when taken over and over again over time. There are even some legal prescription drugs that can induce severe depression. Corticosteroids, birth control pills and some cancer drugs are among them. MDMA itself is not a neurotoxin, it is when the depleted serotonin neurons, and reuptake sites begin to take up dopamine, and then metabolize it into toxic metabolites that destroys serotonin axon terminals...a small dose of a SSRI a few hours after taking MDMA will prevent any damage by blocking the dopamine from entering the reuptake sites. pure MDMA injected into the brains of primates does not cause serotonin axon damage all studies concerning MDMA neurotoxicity involved massive doses given daily over an extended period of time (interesting how the FDA approved pondomin, which causes the *exact* same axon damage, for *daily* and
*extended* use, yet MDMA is an illicit and *harmful* neurotoxin)



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